Pharma & Bulk Drugs
Vacuum controlled processes that separate ingredients without degrading them
Pharmaceutical Industry Solutions
The pharmaceutical industry employs several vacuum controlled processes that separate ingredients without degrading them.
Pharmaceutical Processes
Some of the processes are
Drying
Vacuum drying processes for pharmaceutical ingredients while maintaining product integrity and quality.
Sterilization
Critical sterilization processes ensuring pharmaceutical products meet stringent safety and purity standards.
Degassing
Removal of dissolved gases from pharmaceutical solutions and formulations under controlled conditions.
Vacuum Distillation
Precise distillation processes under vacuum conditions for separation and purification of compounds.
Crystallization
Controlled crystallization processes for pharmaceutical active ingredients and intermediates.
Lyophilization/Sublimation/Freeze Drying
Advanced freeze-drying processes for preserving sensitive pharmaceutical compounds and biologics.
Vacuum Pump Technology
Pressure & Vacuum Capabilities
Vacuum pumps are valued for the extent of vacuum they can reach and for the volume of gas they can pump in a unit of time. Actually two or more different types of pumps may be needed to be used in series to attain the desired degree of vacuum.
Rotary Oil-Seal Pump Operation
In the rotary oil-seal pump, gas is sucked into the first chamber through the opening intake port by the rotor. A sliding vane partitions the first chamber from the second chamber. The compressed gas that has been moved from one position to another is pushed out of the exit port through the valve.
Valve and Rotor Contact
The valve prevents the gas from flowing back. The valve and the rotor contact point are oil-sealed. Since each revolution sweeps out a fixed volume, it is called a constant-displacement pump.
Alternative Pump Technologies
Other mechanical pumps are the rotary blower pump, which operates by the propelling action of one or more rapidly rotating lobe like vanes, and the molecular drag pump, which operates at very high speeds, as much as 16,000 rpm. Pumping is accomplished by imparting a high momentum to the gas molecules by the impingement of the rapidly rotating body.
Pump Types and Specifications
Rotary Oil-Seal Pump
Type: Constant-displacement
Operation: Fixed volume per revolution
Sealing: Oil-sealed contact points
Application: Primary vacuum generation
Rotary Blower Pump
Type: Propelling action
Operation: Rapidly rotating lobe vanes
Configuration: One or more vanes
Application: High volume pumping
Molecular Drag Pump
Speed: Up to 16,000 rpm
Operation: High momentum transfer
Mechanism: Rapidly rotating body
Application: Ultra-high vacuum
Pharmaceutical Industry Applications
API Manufacturing
Bulk Drug Production
Vaccine Production
Biotechnology
Fine Chemicals
Research & Development
Quality Control
Formulation
Technical Specifications
Vacuum Performance
Ultimate Vacuum: 10⁻³ to 10⁻⁹ mbar
Pumping Speed: 0.5 to 5000 m³/h
Operating Pressure: Atmospheric to high vacuum
Gas Compatibility: Inert and reactive gases
Operating Conditions
Temperature: -40°C to +200°C
Materials: Pharmaceutical grade
Contamination: Oil-free options available
Validation: GMP compliant
Standards & Compliance
FDA: 21 CFR Part 11 compliant
GMP: Good Manufacturing Practice
USP: United States Pharmacopeia
ATEX: Explosion protection
Key Benefits for Pharmaceutical Applications
Product Quality
Ingredient Preservation
Vacuum processes separate ingredients without degrading them, maintaining pharmaceutical quality.
Contamination Control
Clean, oil-free vacuum solutions prevent contamination of pharmaceutical products.
Precise Control
Accurate vacuum control for consistent pharmaceutical manufacturing processes.
Process Efficiency
Multiple Process Capability
Single pump systems can handle multiple pharmaceutical processes efficiently.
Energy Efficiency
Optimized pump designs reduce energy consumption in pharmaceutical operations.
Scalable Solutions
Pump systems available for laboratory to production scale applications.
Need Pharmaceutical Vacuum Solutions?
Send us an inquiry for the right type pump that you require for your pharmaceutical and bulk drug manufacturing processes. Our vacuum pump solutions are designed to meet the stringent requirements of the pharmaceutical industry.